Lead Poisoning Pathophysiology: The Sally Larsen Case Study

This assignment is intended to help you learn to analyze and explain the impact of environmental agents on cellular and tissue biology and thus the associated pathological phenomena and details compared to normal physiology. Overview Patients presenting with symptoms such as nausea, vomiting, headache, fever, and abdominal pain could have one of many diseases and conditions. For this discussion, we are going to explore heavy metal toxicity, including the pathophysiology and manifestations of this condition. Your Patient: Sally Larsen Sally Larsen, a 16-year-old, presents with severe abdominal pain, loss of appetite, nausea, and vomiting. Her family owns a pottery business, and she has always been in the studio since she was a child. In recent years, she has helped make pots and other items for sale. One year ago, she was diagnosed with severe abdominal pain and acute appendicitis. After her appendectomy, the abdominal pain persisted. It is determined that Sally has lead poisoning. Action Items 1. Read the Discussion Guidelines. 2. Read the scenario in the Overview section. 3. Reflect and Respond: Part I • Explain the impact of lead exposure on cellular and tissue biology and thus the associated pathological phenomena and details compared to normal physiology. Support your response with references, including your textbook and a minimum of three other credible, scholarly sources. Part II • Review the following: As you come to the end of the visit with Sally, her mother has a couple of questions. Sally's mother inquires how common lead poisoning is and its most common source. She also asks about lead poisoning in young children. She explains that they have a niece who is eight years old that has spent a lot of time with them in the studio over the last two years. Mrs. Larsen asks if her niece should be tested and how young children are evaluated for lead. She also asks what level of poisoning requires follow-up action. Finally, she wonders how lead poisoning is treated and when treatment is recommended. • Respond: Please answer Mrs. Larsen's questions. Give your rationale and substantiate them with references, including your textbook and a minimum of 3 other credible, scholarly sources. Part III • Finally, read your peers' work. You do not have to comment on their posts (although you may if you wish to). However, after reading your classmates' posts, return to your own posting. Make a reply to your original work and tell what you learned from reading the work of your peers. Briefly explain what you would alter in your original work, if anything. If not, why not? (For example, after reading others' work, does it seem like you overlooked anything? Would you change anything you wrote? Or if you are satisfied with your original work, did you also gain insights from seeing the way your peers approached the case?)